Phenibut is a great substance, no doubt. It is loved by many for its incredible anti-anxiety action which confirmed by thousands of good feedbacks.  However, it can be misused. Here Is the Phenibut review on side effects, recommended dosage and overdose symptoms. Things you should know to take Phenibut safely without any problems.


Phenibut dosage

Here is the official recommended dosage from the manufacturer:

  • Inside, after a meal.
  • Dosage for adults is 250-500mg three times a day.
  • The maximum single dose in adults 750mg, for patients older than 60 years – 500mg.
  • The course of treatment 2-3 weeks. If necessary, the course may be extended for up to 4-6 weeks. Duration of therapy is determined by a doctor taking into account the symptoms of the disorder, drug tolerability and the result achieved.
  • For alcohol withdrawal relief – 250-500mg three times through the day and 750mg overnight with a gradual reduction to the typical adult daily dosage.
  • For the treatment of vertigo with vestibular disorders of vascular and traumatic genesis – 250mg three times a day with 12 days long treatment.
  • To prevent motion sickness – 250-500mg one hour before the departure time.


Phenibut side effects

Information from manufacturer’s manual:

  • Possible Effects on the Nervous System: drowsiness (at the beginning of the treatment), irritability, anxiety, headache, dizziness, agitation.
  • Nausea.
  • Allergic reactions (rash, itching).
  • During long-term use in high dosage – Hepatotoxicity.
  • Contraindications: Liver diseases, pregnancy, and lactation, Hypersensitivity to the drug.
  • Use with caution if you have erosive lesions of gastrointestinal tract


Toxicity and Overdose

Phenibut toxicity is low. It absorbs well in the digestive tract and disperses evenly in the body. About 0.1% of Phenibut able to reach the brain tissue (this percentage is significantly larger for young and elderly patients). Drug metabolism occurs in the liver. Phenibut does not accumulate in the body and are excreted from the body within 24 hours after ingestion. Excessive dosage may lead to poisoning.

Possible overdose symptoms are:

  • Sleepiness.
  • Nausea.
  • Increased heart rate, low blood pressure.
  • Impaired Kidneys function

Prolonged overdosed usage may lead to fatty liver dystrophy and liver dysfunctions. Don’t mix it with alcohol.


Phenibut addiction and withdrawal

Phenibut can be addictive if taken not responsible. It is better to take it only infrequently, not more than a couple of days per week. A withdrawal syndrome may occur if you abruptly stop taking Phenibut after a long cycle, so it’s good to use it for shorter cycles, or after prolonged usage lower your dosage gradually until you are taking none.

The side effects, addiction and withdrawal syndrome described above, however, is rare. Most people take Phenibut at significant doses without experiencing any side effects. After all, different people react to Phenibut (as well as to other substances) in various ways. Always start with the lower dosage. Responsible use is a key to the pleasant results!